Duties include: Lead chemical manufacturing processes & facility equipment for transfer of new drug products into multi-modal (RNA editing, Anti-sense oligonucleotide, SIRNA) clinical stage stereo pure Oligonucleotide manufacturing plant. Lead teams in design, implementation, & qualification of cGMP oligonucleotide manufacturing process, plant equipment, & control systems.
Requirements:
- MS/foreign equivalent in Chemical Engineering/related field with 6 years' experience in process engineering with focus on oligonucleotide manufacturing technology
- Experience must include 2 years' experience in:
- Process safety evaluation of equipment & utilities handling novel chemistries such as PN-modified stereopure oligonucleotides & sodium azide
- API experience in design & development of flow reaction equipment for liquid phase reactions such as cleavage & deprotection, & Phosphoramidite synthesis
(May be gained concurrently)
Apply at: https://ectt.fa.us2.oraclecloud.com/hcmUI/CandidateExperience/en/sites/CX_1/requisitions/preview/368
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